Obesity Clinical Research
Clinical research is patient-oriented research. Research may be conducted in human
volunteers or on samples from humans. NIH-funded studies are carefully designed
to answer specific medical questions while protecting participants´ safety.
Well conducted clinical trials are the fastest and safest way to find improved treatments
and preventions for diseases. Clinical trials or interventional trials determine
whether experimental preventions, treatments, or new ways of using known therapies
are safe and effective under controlled conditions. Observational or natural history
studies examine health issues and disease development in groups of people or populations.
Understanding Clinical Trials
Multi-site Clinical Trials
Recruiting
- The Action to Control
Cardiovascular Disease Risk in Diabetes (ACCORD)
NIDDK is co-funding a study to test best ways to lower risk of heart disease and
stroke in adults with type 2 diabetes.
- Bypass Angioplasty Revascularization
Investigation (BARI) 2 Diabetes
| www.bari2d.org/
This study, co-funded by NIDDK, aims to determine the best therapies for people
with type 2 diabetes and heart disease.
- Longitudinal Assessment
of Bariatric Surgery (LABS)
The Longitudinal Assessment of Bariatric Surgery (LABS) is conducting coordinated
clinical, epidemiological, and behavioral research in the field of bariatric surgery
through the development of common clinical protocols and a bariatric surgery database.
Recruitment anticipated in Fall 2004.
- SEARCH for Diabetes in Youth Study
| www.searchfordiabetes.org/
This study, co-funded by NIDDK, will determine the prevalence of diabetes in children
in six areas of the U.S. and help clarify trends in the development of diabetes
in youth.
- TODAY Trial
The TODAY (Treatment Options for type 2 Diabetes in Adolescents and Youth) study,
which seeks to identify the best treatment of type 2 diabetes in children and teens,
has begun in 12 medical centers and affiliated sites around the country.
- Urinary Incontinence Treatment Network
(UITN)
The UITN is conducting long-term studies of commonly used surgical, pharmacological,
and behavioral approaches to managing stress and mixed urinary incontinence in women.
- ClinicalTrials.gov
For other studies in diabetes, search this comprehensive database.
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Ongoing - No Longer Recruiting
Completed
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Follow-up Studies
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Clinical Research
- Beta Cell Biology Consortium
(BCBC)
The mission of the Beta Cell Biology Consortium (BCBC) is to facilitate interdisciplinary
approaches that will advance the understanding of pancreatic islet development and
function.
- Endocrine Pancreas
Consortium
The Endocrine Pancreas Consortium was formed in late 1999 to derive and sequence
cDNA libraries enriched for rare transcripts expressed in the mammalian endocrine
pancreas.
- International
Type 2 Diabetes Linkage Analysis Consortium
This consortium is organizing international efforts to combine existing data sets
for linkage analysis in an effort to map genes for type 2 diabetes. In addition,
the availability of a large number of samples allows for analysis of individual
ethnic groups for predominant diabetes susceptibility genes.
- NIDDK Central Repositories
The Biosample, Genetics, and Data Repositories have been established to store biosamples
and data collected in designated NIDDK-funded clinical studies. The purpose of the
NIDDK Central Repositories is to expand the usefulness of these studies by allowing
a wider research community to access these materials beyond the end of the study.
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Last Updated: 6/30/2004
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