Wednesday, September 17, 2008 |
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| 8:30 – 8:30 a.m. | Registration |
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SESSION I: INTRODUCTION AND BACKGROUND |
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| 8:30 – 8:45 a.m. | Welcome
Judith Fradkin, M.D., Division Director, Diabetes, Endocrinology and Metabolism, National Institute of Diabetes and Digestive and Kidney Diseases,
National Institutes of Health
Office of Rare Diseases, National Institutes of Health |
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| 8:45 – 9:05 a.m. | Diabetic Neuropathy and Foot Disease: A Medical, Social, and Economic Disaster with Potential for Prevention
Andrew Boulton, M.D., F.R.C.P., University of Manchester |
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| 9:05 – 9:10 a.m. | Discussion |
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| 9:10 – 9:30 a.m. | Charcot Neuroarthropathy: Historical Aspect
Lee Sanders, D.P.M., Lebanon VA Medical Center |
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| 9:30 – 9:35 a.m. | Discussion |
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| 9:35 – 9:55 a.m. | The Diabetic Charcot Foot: Definition, Classification, and Staging
Robert Frykberg, D.P.M., M.P.H., Carl T. Hayden Medical Center |
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| 9:55 – 10:05 a.m. | Discussion |
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| 10:05 – 10:25 a.m. | Epidemiology of Charcot Neuroarthropathy
David Margolis, M.D., Ph.D., University of Pennsylvania |
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| 10:25 – 10:35 a.m. | Discussion |
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| 10:35 – 10:55 a.m. | Break |
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| 10:55 – 11:05 a.m. | Submitted Abstract Presentation: Quality of Life of Patients Affected by Charcot Neuroarthropathy
Loretta Vileikyte, M.D., Ph.D., University of Manchester |
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| 11:05 – 11:10 a.m. | Discussion |
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| 11:10 – 11:20 a.m. | Submitted Abstract Presentation: The Association Between Obesity and Charcot Neuroarthropathy in a Diabetic Population
Elly Budiman-Mak, M.D., M.P.H., Loyola University Stritch School of Medicine and Edward Hines Jr. VA Hospital |
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| 11:20 – 11:25 a.m. | Discussion |
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SESSION II: UPDATE ON CALCIUM AND BONE BIOLOGY |
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| 11:25 – 11:45 a.m. | Bone Biology and Control Mechanisms: Normal Bone Turnover, Fracture Healing, and Possible Abnormalities in Charcot Neuroarthropathy
Greg Mundy, M.D., Vanderbilt University |
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| 11:45 – 11:55 a.m. | Discussion |
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| 11:55 – 12:15 p.m. | The RANKL-OPG System and the Bone Vascular Interphase
Lorenz Hofbauer, University Hospital Carl Gustav Carus at the Technical University of Dresden |
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| 12:15 – 12:25 p.m. | Discussion |
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| 12:25 – 12:35 p.m. | Submitted Abstract Presentation: Radiographic Correlates of Charcot Neuroarthopathy Deformity Reflect Midfoot Function and Calcaneal Bone Mineral Density
Mary K. Hastings, D.P.T., P.T., A.T.C., Washington University School of Medicine |
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| 12:35 – 12:40 p.m. | Discussion |
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| 12:40 – 12:50 p.m. | Submitted Abstract Presentation: The Role of the Proinflammatory Cytokine TNF-α in Acute Charcot Neuroarthropathy
Michael Edmonds, M.D., King�s College Hospital, London, UK |
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| 12:50 – 12:55 p.m. | Discussion |
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| 12:55 – 2:00 p.m. | Lunch (on your own) |
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SESSION III: PATHOGENESIS AND DIAGNOSIS |
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| 2:00 – 2:20 p.m. | Aetiopathogenesis of Charcot Neuroarthropathy: An Update for 2008
William Jeffcoate, M.D., University of Nottingham and City Hospital |
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| 2:20 – 2:30 p.m. | Discussion |
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| 2:30 – 2:50 p.m. | Risk Factors for Charcot Neuroarthropathy
Michael Edmonds, M.D., University of London |
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| 2:50 – 3:00 p.m. | Discussion |
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| 3:00 – 3:20 p.m. | Advances in Understanding of Charcot Disease and Implications for Diabetes in General
William Jeffcoate, M.D., University of Nottingham and City Hospital |
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| 3:20 – 3:30 p.m. | Discussion |
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| 3:30 – 3:50 p.m. | Break |
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| 3:50 – 4:10 p.m. | Goals of Therapy of Charcot Fractures and Assessment of Outcomes
Peter R. Cavanagh, Ph.D., D.Sc., University of Washington |
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| 4:10 – 4:20 p.m. | Discussion |
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| 4:20 – 4:30 p.m. | Submitted Abstract Presentation: Association Between Osteoprotegerin G1181C and T245G Polymorphisms and Charcot Neuroarthropathy
Dario Pitocco, M.D., Catholic University, Rome, Italy |
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| 4:30 – 4:35 p.m. | Discussion |
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| 4:35 – 4:45 p.m. | Submitted Abstract Presentation: Atlas-Based Quantitative Imaging in Charcot Neuroarthropathy
David R. Sinacore, Ph.D., P.T., F.A.P.T.A., Washington University School of Medicine |
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| 4:45 – 4:50 p.m. | Discussion |
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Thursday, September 18, 2008 |
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SESSION IV: MANAGEMENT |
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| 9:00 – 9:20 a.m. | Methods for Early Diagnosis
Luigi Uccioli, M.D., University of Rome |
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| 9:20 – 9:30 a.m. | Discussion |
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| 9:30 – 9:50 a.m. | Current Medical Management of Acute CN
Jan Ulbrecht, M.D., The Pennsylvania State University |
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| 9:50 – 10:00 a.m. | Discussion |
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| 10:00 – 10:20 a.m. | The Surgical Management of Diabetic Charcot Arthropathy: Evidence-Based Medicine or Lack Thereof?
Dane Wukich, M.D., University of Pittsburgh Medical Center |
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| 10:20 – 10:30 a.m. | Discussion |
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| 10:30 – 10:50 a.m. | Break |
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| 10:50 – 11:10 a.m. | Achieving Therapy for Rare Diseases
William Gahl, M.D., Ph.D., National Human Genome Research Institute |
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| 11:10 – 11:20 a.m. | Discussion |
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| 11:20 – 11:30 a.m. | Submitted Abstract Presentation: Outcome Evaluation of Charcot Reconstruction by Monitoring Dynamic Behavior of Plantar Pressure Distribution
Bijan Najafi, Ph.D., Rosalind Franklin University of Medicine and Science |
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| 11:30 – 11:35 a.m. | Discussion |
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| 11:35 – 11:45 a.m. | Submitted Abstract Presentation: Reconstruction of the Charcot Ankle Utilizing External Ring Fixation
Howard M. Kimmel, D.P.M., M.B.A., Louis Stokes Department of Veterans Affairs |
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| 11:45 – 11:50 a.m. | Discussion |
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| 11:50 – 12:00 p.m. | Submitted Abstract Presentation: Charcot Foot and Nerve Compression
D. Scott Nickerson, M.D., F.A.A.O.S., Consultant to Northeast Wyoming Wound Clinic |
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| 12:00 – 12:05 p.m. | Discussion |
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| 12:05 – 12:25 p.m. | Wrap-up |
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| 12:25 p.m. | Adjourn |
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